Statuzer is a multi-platform Twitter Client running through Air. Of course, as you might expected it, Statuzer is beta.
It offers Multi-account for Twitter, identi.ca, StatusNet (former laconi.ca) and Hellotipi; multi-columns and Single modes; MP3 playing directly from Song.ly & tra.kz tweets; free and legal music search from Jamendo; direct thumbs for twitpic, yfrog, flickr, youtube and vimeo; image and webcam upload to twitpic and Twitter profile image; URLs preview; and Ping.fm integration.
