Sickbeard Launcher is a Mac App that makes using SickBeard easier than ever. Simply open the app and a dialog will appear prompting you to select the path where your Sickbeard.py file is located. After you select the path, you're ready to go.
Wineskin Winery creates Mac OS X ports/wrappers for Windows programs/games, with an easy-to-use GUI, integrated Wine, X11 and an installer.