PhyloCoco is a simple tool for molecular phylogenetic estimation.
PhyloCoco is a simple tool for molecular phylogenetics able to rebuild phylogenies from DNA sequences under the likelihood or the minimum evolution criterion.
Main Features:
-The GTR model of DNA evolution.
-General additive distances [X. Gu and W.H. Li, A general additive distance with time-reversibility and rate variation among nucleotide sites, PNAS 93 (1996), 4671–4676].
-Random Directions, Brent’s algorithm and Random Search for unconstrained non-linear optimization of the likelihood parameters.
-Very Large-Scale Neighborhood (VLSN) search for the topological optimization.
-Iterated Local Search (ILS) to explore the solution space.
-Ant Colony Optimization (ACO) to explore the solution space under the minimum evolution criterion [D. Catanzaro, R. Pesenti and M. C. Milinkovitch, An ant colony optimization algorithm for phylogenetic estimation under the minimum evolution principle, appeared in BMC Evolutionary Biology].
-FigTree to display the resulting phylogeny.
Mall Creeps
Fighting The Infected Horde
The Immersive 2D Sandbox Platformer Game You Have to Try
Premium survival horror
One of the best Resident Evil games
An epic battle royale game
The First Game in the Call of Duty: Black Ops Series
Comments