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PhyloCoco 2.3

Free A simple tool for molecular phylogenetic estimation.
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Latest version:
2.3 See all
Developer:
Collect

PhyloCoco is a simple tool for molecular phylogenetic estimation.

PhyloCoco is a simple tool for molecular phylogenetics able to rebuild phylogenies from DNA sequences under the likelihood or the minimum evolution criterion.

Main Features:

-The GTR model of DNA evolution.

-General additive distances [X. Gu and W.H. Li, A general additive distance with time-reversibility and rate variation among nucleotide sites, PNAS 93 (1996), 4671–4676].

-Random Directions, Brent’s algorithm and Random Search for unconstrained non-linear optimization of the likelihood parameters.

-Very Large-Scale Neighborhood (VLSN) search for the topological optimization.

-Iterated Local Search (ILS) to explore the solution space.

-Ant Colony Optimization (ACO) to explore the solution space under the minimum evolution criterion [D. Catanzaro, R. Pesenti and M. C. Milinkovitch, An ant colony optimization algorithm for phylogenetic estimation under the minimum evolution principle, appeared in BMC Evolutionary Biology].

-FigTree to display the resulting phylogeny.

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