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Manage one or multiple Twitter accounts on your Mac.

Rocket.Chat is a Web Chat Server, developed in JavaScript.

An unofficial and privacy-focused Facebook Messenger application.

Use the Pushbullet web app without opening your browser.

Use the WhatsApp application on your Mac OS system.

Yakyak is an open source chat client for Google Hangouts.

Windows

Windows Mac

Mobile-Flex LLC

Mobile-Flex

Free

It creates a custom Windows desktop for the end-user.